Thursday, 2 July 2015

CARDIO-FIT: Increased Fitness Linked to Dose-Dependent Reduction in Atrial-Fibrillation Symptoms, Recurrence

An  observational show that Cardiorespiratory Fitness (CRF) helps not only with relieving symptoms of atrial fibrillation (AF), but it also predicted recurrence in patients who were obese. The study with 308 patients showed that those who had high CRF at baseline were significantly more likely to have arrhythmia-free survival at follow-up more than 4 years later than the participants who had low or even adequate cardiofitness.

After patients enrolled in a tailored exercise programme, both CRF fitness gain and weight loss were associated with significantly improved outcomes. In addition, the patients who gained at least two peak metabolic equivalents (METs) had a greater decrease in AF burden and symptom severity and more incidence of arrhythmia-free survival with or without rhythm control vs those with fewer METs gained—and a twofold greater probability of arrhythmia-free survival.

The results were presented at a late-breaking clinical-trial session at the European Heart Rhythm Association (EHRA) EUROPACE-CARDIOSTIM 2015 meeting and were simultaneously published in the Journal of the American College of Cardiology. 

"This study emphasizes the prescriptive role of exercise in managing patients with afib, particularly in a strategy of rhythm control,"  said lead author Dr Rajeev Pathak of the University of Adelaide and Royal Adelaide Hospital in Australia.

Sherldine Tomlinson.